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DNA polymerase I: Quiz

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Question 1: Moreover, it is insufficiently processive to copy an entire ________, as it falls off after incorporating only 25-50 nucleotides.
GeneticsGenomicsDNAGenome

Question 2: DNA polymerase I obtained from E. coli is used extensively for ________ research.
Transcriptional regulationEpigeneticsMolecular biologyPost-transcriptional regulation

Question 3: A 3' -> 5' (reverse) ________ activity that mediates proofreading
ExonucleaseRestriction enzymeRNase PPhosphodiesterase

Question 4: DNA Polymerase I (or Pol I) is an enzyme that participates in the process of ________ in prokaryotes.
Primer (molecular biology)TelomeraseReplication forkDNA replication

Question 5: A 5' -> 3' (forward) exonuclease activity mediating nick translation during ________.
DNA repairHomologous recombinationCell cycleGene

Question 6: In E. coli and many other bacteria, the ________ which encodes Pol I is known as polA.
DNAEvolutionGeneGenetics

Question 7: Discovered by ________ in 1956[1], it was the first known DNA polymerase (and, indeed, the first known polymerase of any kind).
Marshall Warren NirenbergArthur KornbergDavid BaltimoreJames D. Watson

Question 8: Fortunately this undesirable enzymatic activity can be simply removed from the holoenzyme to leave a useful molecule called the Klenow fragment, widely used in ________.
Post-transcriptional regulationMolecular biologyTranscriptional regulationEpigenetics

Question 9: It was initially characterized in ________, although it is ubiquitous in prokaryotes.
Helicobacter pyloriEscherichia coliPseudomonas aeruginosaPathogenic bacteria







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