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Cytotoxicity: Quiz


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Question 1: Three groups of cytotoxic ________ are distinguished:
Adaptive immune systemLymphocyteThymocyteImmune system

Question 2: Antibody-dependent cell-mediated cytotoxicity (ADCC) describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an ________.
Immune systemAutoantibodyAdaptive immune systemAntibody

Question 3: The cells may undergo ________, in which they lose membrane integrity and die rapidly as a result of cell lysis.

Question 4: [3] Such ATP-based assays include bioluminescent assays in which ATP is the limiting reagent for the ________ reaction.
Linoleate 11-lipoxygenaseArachidonate 12-lipoxygenaseArachidonate 15-lipoxygenaseLuciferase

Question 5: Lymphocyte-mediated cytotoxicity, on the other hand, does not have to be mediated by antibodies; nor does complement-dependent cytotoxicity (CDC), which is mediated by the ________.
Classical complement pathwayComplement systemAlternative complement pathwayMannan-binding lectin pathway

Question 6: Cytotoxicity is the quality of being ________ to cells.
PoisonLead poisoningMercury poisoningToxicity

Question 7: from the puff adder or ________).
CaliforniaBrown recluse spiderUnited StatesSpider bite

Question 8: Examples of toxic agents are a ________, an immune cell or some types of venom (e.g.
CarbonChemical substanceOxygenChemistry

Question 9: The cells can stop actively growing and dividing (a decrease in cell viability), or the cells can activate a genetic program of controlled cell death (________).
Apoptosis-inducing factorTranscription factorApoptosisSignal transduction


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