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Creatinine: Quiz

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Question 1:
What is the chemical name of Creatinine (IUPAC)
2-amino-1-methyl-5H-imidazol-4-one
Poly[imino(2S)-2-amino-1-oxo-1,6-hexanediyl]
-5-amino-1-cyclohexa-1,3-dienecarboxylic acid
2-amino-3-propanoic acid

Question 2: Creatinine (from the Greek κρέας, flesh) is a break-down product of creatine phosphate in ________, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
FasciaTorsoHead and neck anatomyMuscle

Question 3: (In the absence of secretion, creatinine behaves like ________.)
InulinFructoseGlucoseStarch

Question 4: ________ - novel marker of kidney function.
DNAC-reactive proteinCystatin CProtein

Question 5: A rise in blood creatinine levels is observed only with marked damage to functioning ________.
KidneyUrinary systemMedullary interstitiumNephron

Question 6: However, in cases of severe ________ dysfunction, the creatinine clearance rate will be "overestimated" because the active secretion of creatinine will account for a larger fraction of the total creatinine cleared.
Endocrine systemKidneyLiverUrinary system

Question 7: A better estimation of kidney function is given by the ________ test.
Renal functionAnion gapNephronRenal physiology

Question 8: A more complete estimation of renal function can be made when interpreting the blood (plasma) concentration of creatinine along with that of ________.
CysteineUreaAmmoniaNitrogen

Question 9: Ketoacids, ________ and trimethoprim reduce creatinine tubular secretion and therefore increase the accuracy of the GFR estimate, particularly in severe renal dysfunction.
RanitidineCimetidineH2 antagonistFamotidine

Question 10: In the United States, creatinine is typically reported in mg/dL, while in ________ and a few European countries μmol/litre may be used.
CanadaUnited KingdomBelizeBarbados







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