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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency: Quiz


Question 1: The single small urethral/vaginal opening at the base or on the shaft of the phallus would be considered a ________ in a male.

Question 2: Levels of 17-hydroxyprogesterone, androstenedione, and ________ may play a role in screening.

Question 3: These clinical features, of course, are those of ________, and a small percentage of women with PCOS are found to have late-onset CAH when investigated.
Congenital adrenal hyperplasia due to 21-hydroxylase deficiencyHypopituitarismAndrogen insensitivity syndromePolycystic ovary syndrome

Question 4: to make it possible for these girls to participate in normal ________ when they grow up
Human sexual behaviorSexual intercoursePregnancyMasturbation

Question 5: It also catalyzes hydroxylation of progesterone to 11-deoxycorticosterone (DOC) in the mineralocorticoid pathway on its way from pregnenolone to ________.

Question 6: ________ in these infants can be extreme—levels of K+ above 10 mEq/L are not unusual—as can the degree of metabolic acidosis.
HypokalemiaRenal tubular acidosisHyperkalemiaDiabetic ketoacidosis

Question 7: The first problem has not yet been entirely solved, but it has been shown that if ________ is taken by a pregnant woman enough can cross the placenta to suppress fetal adrenal function.

Question 8: ________ are replaced in all infants with salt-wasting and in most patients with elevated renin levels.
CorticosteroidATC code HMineralocorticoidGlucocorticoid

Question 9: On the other hand, adrenal androgens are readily converted to ________, which accelerates bone maturation and can lead to early epiphyseal closure.

Question 10: Central precocious puberty is suppressed when appropriate by ________.

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