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Coeliac disease: Quiz
  
  
  

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Question 1: Calcium and vitamin D malabsorption (and compensatory secondary ________) may cause osteopenia (decreased mineral content of the bone) or osteoporosis (bone weakening and risk of fragility fractures).
PseudohypoparathyroidismHyperparathyroidismOsteitis fibrosa cysticaPrimary hyperparathyroidism

Question 2: [68] Some have persisting digestive symptoms or ________, mouth ulcers, osteoporosis and resultant fractures.
Bullous pemphigoidPemphigusDermatitis herpetiformisPsoriasis

Question 3: Coeliac disease leads to an increased risk of both ________ (small intestine cancer) and lymphoma of the small bowel (enteropathy-associated T-cell lymphoma or EATL).
Krukenberg tumorICD-10 Chapter II: NeoplasmsSquamous cell carcinomaAdenocarcinoma

Question 4: Stored biopsies from suspected coeliac patients have revealed that ________ deposits in the subclinical coeliacs are detected prior to clinical disease.
InflammationCell-mediated immunityAutoimmunityAutoantibody

Question 5: [2] However, about 20–30% of people without coeliac disease have inherited an ________2 allele.
HLA-DQB1HLA-DQHuman leukocyte antigenMajor histocompatibility complex, class II, DQ alpha 1

Question 6: [2][30] However, not all prolamins will cause this immune reaction, and there is ongoing controversy on the ability of ________ (the prolamin found in oats) to induce this response in coeliac disease.
OatWheatBarleyMaize

Question 7: Gee highlighted particular success with a child "who was fed upon a quart of the best Dutch ________ daily." However, the child could not bear this diet for more than one season.
ScallopAbaloneMusselOyster

Question 8: If alternative causes have been eliminated, steroids or immunosuppressants (such as ________) may be considered in this scenario.
AzathioprineTacrolimusMethotrexateLeflunomide

Question 9: Among the 6% of European coeliacs that do not have DQ2.5 (cis or trans) or DQ8 (encoded by the ________ DQA1*03:DQB1*0302), 4% have the DQ2.2 isoform, and the remaining 2% lack DQ2 or DQ8.
HaplotypeHardy–Weinberg principleAlleleHaplogroup

Question 10: Growth failure and/or pubertal delay in later childhood can occur even without obvious bowel symptoms or severe ________.
ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseasesVitaminMalnutritionObesity
















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