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Clindamycin: Quiz


Question 1: Most aerobic Gram-negative bacteria (such as Pseudomonas, Legionella, ________ and Moraxella) are resistant to clindamycin,[12][13] as are the facultative anaerobic Enterobacteriaceae.
CholeraTyphoid feverHaemophilus influenzaePathogenic bacteria

Question 2: High doses (both intravenous and oral) may cause a metallic taste, and topical application may cause ________.
Contact dermatitisSystemic lupus erythematosusAtopic dermatitisUrticaria

Question 3: The combination of clindamycin and quinine is the standard treatment for severe ________.
MalariaICD-10 Chapter I: Certain infectious and parasitic diseasesToxoplasmosisBabesiosis

Question 4:
What is the elimination half life of Clindamycin?
2 to 3 hours
12 days - Multiple Dose; 120-170 hours - Single Dose
Approximately 5 to 6 hours in adults
2u20133 hours

Question 5: Clindamycin may prolong the effects of ________.
Neuromuscular-blocking drugNicotinic antagonistOrphenadrineAnticholinergic

Question 6:
How is Clindamycin excreted?
Biliary and renal
70-90% unchanged in urine, 1.3ml/kg/min t1/2 2- 4 hours
Renal 40u201350% ,
Renal, very slow

Question 7: ________ is a potentially-lethal condition commonly associated with clindamycin, but which also occurs with other antibiotics.
Clostridial necrotizing enteritisPseudomembranous colitisGastroenteritisWhipple's disease

Question 8: It does so by binding preferentially to the 23S rRNA of the large bacterial ________ subunit.
MitochondrionRibosomeCell (biology)Cell nucleus

Question 9: Clindamycin has been proven to decrease the risk of premature births in women diagnosed with ________ during early pregnancy to about a third of the risk of untreated women.
VaginitisPelvic inflammatory diseaseBacterial vaginosisCervicitis

Question 10: [3] In patients with hypersensitivity to ________, clindamycin may be used to treat infections caused by susceptible aerobic bacteria as well.
PenicillinCephalosporinBeta-lactam antibioticCycloserine

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