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Citrate: Quiz


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Question 1: After the ________ forms acetyl CoA, from pyruvate and five cofactors (Thiamine pyrophosphate, lipoamide, FAD, NAD+, and CoA), citrate synthase catalyzes the condensation of oxaloacetate with Acetyl CoA to form citrate.
Mitochondrial trifunctional proteinPyruvate dehydrogenase complexCholesterol side-chain cleavage enzymeOxoglutarate dehydrogenase

Question 2: Citric acid can act as a mild ________ agent.
Chelation therapyEDTALipoic acidChelation

Question 3: As a weak acid, citrate can be used as a component in ________, including the commonly used SSC 20X hybridization buffer[1].
Acid-base extractionBuffer solutionAcid dissociation constantBase (chemistry)

Question 4: ________ (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin)
AnticoagulantWarfarinDirect thrombin inhibitorLow molecular weight heparin

Question 5: Since citric acid is a multifunctional ________, intermediate ions exist, hydrogen citrate ion, HC6H5O72− and dihydrogen citrate ion, H2C6H5O7.
Acid dissociation constantAcidOxygenAcid–base reaction

Question 6: A citrate can refer either to the conjugate base of ________, (C3H5O(COO)33−), or to the esters of citric acid.
Citric acidAcetic acidEthanolCarbon dioxide

Question 7: bivalent: Hirudin (________, Lepirudin, Desirudin)

Question 8: High concentrations of cytosolic citrate can inhibit phosphofructokinase, catalyst of one of the rate-limiting steps of ________.
GluconeogenesisMetabolismCarbohydrate metabolismGlycolysis

Question 9: coumarins: Acenocoumarol • Coumatetralyl • Dicoumarol (Dicumarol) • Ethyl biscoumacetate • Phenprocoumon • ________

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