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Carcinoid syndrome: Quiz


Question 1: For localization of both primary lesions and metastasis, the initial imaging method is Octreoscan, where 111Indium labelled somatostatin analogues (octreotide) are used in ________ for detecting tumors expressing somatostatin receptors.
RadiologyNuclear medicineSurgeryMedical school

Question 2: Carcinoid tumors are discrete, yellow, well-circumscribed tumors that can occur anywhere along the ________ and in the lung.
Ascending cholangitisColorectal cancerPeritonitisHuman gastrointestinal tract

Question 3: Other associated symptoms are nausea, and ________.
Hepatic encephalopathyVomitingAbdominal painDiarrhea

Question 4: Carcinoid tumors produce the vasoactive substance, ________.

Question 5: [3] Secretory ________ and abdominal cramps are also characteristic features of the syndrome.
VomitingDiarrheaTraveler's diarrheaGastroenteritis

Question 6: The pathogenesis of the cardiac lesions and the bronchoconstriction is unknown, but the former probably involves activation of serotonin ________ by serotonin.
5-HT2C receptor5-HT2A receptor5-HT2B receptor5-HT1A receptor

Question 7: In most patients, there is an increased urinary excretion of 5-HIAA (5-hydroxyindoleacetic acid), a degradation product of ________.

Question 8: Carcinoids are tumors of neuroendocrine nature, that originate in the cells of the ________ and are characterized by production of serotonin (5-hydroxytryptamine; 5-HT).

Question 9: Median detection rates with octreoscan are about 89%, in contrast to other imaging techniques such as ________ and MRI with detection rates of about 80%.
Medical radiographyCT pulmonary angiogramX-ray computed tomographyMagnetic resonance imaging

Question 10: The latter is further converted to bradykinin, one of the most powerful ________ known.
Calcium channel blockerAntianginalBeta blockerVasodilation


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