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Carboplatin: Quiz

  

Question 1:
What is the molecular weight of Carboplatin?
230.672 g/mol
344.248 g/mol
234.380 g/mol
371.249 g/mol

Question 2: Cisplatin and carboplatin, as well as oxaliplatin, interact with ________, akin to the mechanism of alkylating agents.
DNAGeneRNAProtein

Question 3: halogenated/ribonucleotide reductase inhibitors (________, Clofarabine, Fludarabine)
MethotrexatePentostatinCladribineBortezomib

Question 4: Carboplatin is a chemotherapy drug used against some forms of ________ (mainly ovarian carcinoma, lung, head and neck cancers).
CarcinogenesisCarcinogenMetastasisCancer

Question 5:
What is the chemical name of Carboplatin (IUPAC)
5-(1R,2S,3S,5S)-3--8-methyl-8-azabicyclo3.2.1octan-2-yl]-3--1,2-oxazole
5-chloro-6'-methyl-3-4-(methylsulfonyl)phenyl-
-3--8-ethyl-
cis-diammineplatinum

Question 6:
What is the elimination half life of Carboplatin?
1u20132 hours
Approximately 5 to 6 hours in adults
1.1-2 hours
?

Question 7: It was introduced in the late 1980s and has since gained popularity in clinical treatment due to its vastly reduced side-effects compared to its parent compound ________.
CarboplatinDoxorubicinCisplatinPaclitaxel

Question 8: Carboplatin differs from cisplatin in that it has a bidentate dicarboxylate (CBDCA) ligand as its leaving group instead of the more labile chloride ________.
HSAB theoryCrystal field theoryCoordination complexLigand
















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