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CREB: Quiz

  

Question 1: Abnormalities of a protein that interacts with the KID domain of CREB, the ________, (CBP) is associated with Rubinstein-Taybi syndrome.
Estrogen receptor alphaEP300Retinoblastoma proteinCREB binding protein

Question 2: CREB (cAMP response element binding) is a ________ that is a transcription factor.
MyosinMetabolismActinProtein

Question 3: CREB also has an important role in the development of ________.
Drug abuseDrug addictionDrug overdoseMood disorder

Question 4: CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (________) proteins.
BCL6Retinoblastoma proteinATF1ATF4

Question 5: Since the effects of protein kinase A on the synthesis of proteins work by activating CREB, the cAMP response element is responsible for modulating the ________ that work by protein synthesis.
G protein-coupled receptor kinaseProtein kinase AProtein kinase CAMP-activated protein kinase

Question 6: This protein kinase translocates to the ________, where it activates a CREB protein.
Cell (biology)MitochondrionCell nucleusEndomembrane system

Question 7: They are necessary for the late stage of ________.
Nervous systemLong-term depressionMemoryLong-term potentiation

Question 8: [3] CREB proteins in neurons are thought to be involved in the formation of long-term memories; this has been shown in the marine snail Aplysia, the fruit fly ________, and in rats.
Caenorhabditis elegansDrosophila melanogasterInsectModel organism

Question 9: It binds to certain ________ sequences called cAMP response elements (CRE) and thereby increases or decreases the transcription, and thus the expression, of certain genes.
RNADNANucleic acidProtein
















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