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CCR5: Quiz

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Question 1: [8] Research from The University of California at Berkeley published in 2003 indicates that ________ may be another candidate for the high level of the mutation in the European population.
AIDSPoliomyelitisSmallpoxInfluenza

Question 2: [11] Multiple studies of HIV-infected persons have shown that presence of one copy of this allele delays progression to the condition of ________ by about 2 years.
Herpes simplexICD-10 Chapter I: Certain infectious and parasitic diseasesAIDSAIDS dementia complex

Question 3: [10] This allele is found in 5-14% of Europeans but is rare in ________ and Asians.
Indigenous peoplesAfrican UnionScramble for AfricaAfrican people

Question 4: ________ was demonstrated in the laboratory not to associate with CCR5.
Helicobacter pyloriYersinia pestisCholeraPlague (disease)

Question 5: fact sheet: CCR5 receptor gene and HIV infection at CDC - (note, author is not a CDC employee, and there is no public domain notice on the page, so this cannot be assumed to be ________)
Public domainCopyrightIntellectual propertyCopyright infringement

Question 6: CCR5 is a gene which encodes the CCR5 protein, "Chemokine (________) receptor 5", a member of the beta chemokine receptors family of integral membrane proteins.
CD154ChemokineCytokineFas ligand

Question 7: CCR5-Δ32 is a deletion mutation of a gene that has a specific impact on the function of ________.
Regulatory T cellT cellCytotoxic T cellT helper cell

Question 8: CCR5 has been shown to interact with CCL5[18][19][20] and ________.
HIVCCBP2CCL3L1Gene

Question 9: In 2008, German doctors announced that an HIV-infected ________ patient had received a bone marrow transplant from a donor who is homozygous for the CCR5-Δ32 trait.
Acute biphenotypic leukaemiaHematological malignancyLeukemiaLeukemoid reaction

Question 10: The normal ________ for this receptor, RANTES, MIP-1β, and MIP-1α, are able to suppress HIV-1 infection in vitro.
Crystal field theoryHSAB theoryLigandCoordination complex







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