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Bupropion: Quiz


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Question 1: ________ symptoms associated with bupropion are rare.
Eating disordersPsychosisPsychiatryMajor depressive disorder

Question 2: Bupropion was invented by Nariman Mehta of Burroughs Wellcome (now ________) in 1969, and the US patent for it was granted in 1974.
VodafoneShire plcAstraZenecaGlaxoSmithKline

Question 3:
What is the chemical name of Bupropion (IUPAC)
methyl N---alaninate

Question 4: [15] Bupropion is more effective than ________ at improving symptoms of hypersomnia and fatigue in depressed patients.
Serotonin reuptake inhibitorTricyclic antidepressantMirtazapineSelective serotonin reuptake inhibitor

Question 5: For the above analysis, the FDA combined the results of 295 trials of 11 antidepressants for psychiatric indications in order to obtain ________ results.
Multiple comparisonsConfidence intervalStatistical significanceStatistical hypothesis testing

Question 6: [7] In 2006, Wellbutrin XL was similarly approved as a treatment for ________.
Bipolar disorderSeasonal affective disorderMajor depressive disorderMelatonin

Question 7: ________-controlled double-blind clinical studies have confirmed the efficacy of bupropion for clinical depression.
AntidepressantNoceboPharmaceutical drugPlacebo

Question 8: [68] In a study of bupropion for ________, a rise of systolic blood pressure by 6 mm Hg and of heart rate by 7 beats per minute (both statistically significant) were observed.
Bipolar disorderSchizophreniaAttention-deficit hyperactivity disorderMajor depressive disorder

Question 9: Bupropion has been approved by the FDA[49] for the prevention of ________.
Bipolar disorderSeasonal affective disorderMajor depressive disorderMelatonin

Question 10:
How is Bupropion excreted?
Fecal and urinary
Nonrenal, renal, and fecal
Renal and fecal, unchanged
Renal , fecal

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