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Buprenorphine: Quiz


Question 1:
How is Buprenorphine excreted?
10-15% unchanged
Biliary, renal
biliary and renal
in feces

Question 2: Buprenorphine hydrochloride is administered by intramuscular injection, ________ infusion, via a transdermal patch, as a sublingual tablet or an ethanolic liquid oral solution.
Intraosseous infusionEnemaIntravenous therapyCream (pharmaceutical)

Question 3: [citation needed] Buprenorphine can be safely taken with prescribed benzodiazepines at normal dosage, as long as the patient is tolerant to either opioids or benzodiazepines, and the drugs are taken in the dosages prescribed and by the ________ prescribed, and not injected.
Intramuscular injectionRoute of administrationIntravenous therapyDosage form

Question 4: One French study showed a higher incidence of fatal overdose in patients who injected both buprenorphine and ________, specifically, temazepam, together.
PropofolBenzodiazepineGABA reuptake inhibitorBarbexaclone

Question 5: Overdose is unlikely in addicted patients or people with tolerance to ________ who use the drug sublingually as meant in the case of Subutex/Suboxone, especially if there is no alcohol involved.

Question 6: Subutex (white color, oval shape, bitter, no active additives) and Suboxone (orange color, hexagonal shaped tablet, orange flavored, one part ________ for every four parts buprenorphine).

Question 7:
What is the elimination half life of Buprenorphine?
10u201328 hours
1.3 to 1.7 hours
20-70, mean 37 hours
2 to 4 hours

Question 8: Possible explanations for this unpleasant taste could be the bitter taste of the buprenorphine itself, or the fact that it acts as a deterrent to abuse and was done intentionally by the pharmaceutical company, ________.
Marks & SpencerLegal & GeneralBritish Sky BroadcastingReckitt Benckiser

Question 9: [citation needed] While the maintenance / abstinence debate is a hot topic and strong arguments in support of both ________ and buprenorphine maintenance have been made, individuals tend to gravitate the alternative that works best for them.
Narcotics AnonymousAddictionDrug addictionTwelve-step program

Question 10: The Suboxone and Subutex preparations were approved for this indication by the ________ FDA in October 2002.
PhilippinesUnited StatesAlaskaCanada

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