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Aztreonam: Quiz


Question 1: ________ trials are currently in progress to measure its delivery in inhaled form, using an ultrasonic nebulizer.
Clinical trial protocolPlacebo-controlled studyClinical trialMedical research

Question 2: Gastrointestinal side effects generally include ________ and nausea and vomiting.
GastroenteritisAbdominal painDiarrheaTraveler's diarrhea

Question 3: Aztreonam has strong activity against susceptible gram-negative bacteria, including ________.
Pseudomonas aeruginosaPathogenic bacteriaHelicobacter pyloriEscherichia coli

Question 4: Reported side-effects include injection site reactions, ________, and rarely toxic epidermal necrolysis.

Question 5: Aztreonam (trade name Azactam) is a synthetic monocyclic beta-lactam ________ (a monobactam), with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum.
Antibiotic misuseATC code J01Nucleic acid inhibitorAntibiotic

Question 6: It is known to be effective against a wide range of bacteria including Citrobacter, Enterobacter, ________, Haemophilus, Klebsiella, Proteus, and Serratia species.
Pathogenic bacteriaPseudomonas aeruginosaEscherichia coliHelicobacter pylori

Question 7: It is resistant to some beta-lactamases, but is inactivated by extended-spectrum ________.
AntibioticAztreonamBeta-lactam antibioticBeta-lactamase

Question 8: [1] Aztreonam is bactericidal but less so than some of the ________.
Beta-lactam antibioticPenicillinCephalosporinVancomycin

Question 9: Aztreonam must be administered ________, as the compound is poorly absorbed when given via the oral route.
EnemaCream (pharmaceutical)Intraosseous infusionIntravenous therapy

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