Antigen-presenting cell: Quiz

Question 1: They do this by chemotaxis, which involves interacting with ________ that are expressed on the surface of cells (e.g., endothelial cells of the high endothelial venules) or have been released as chemical messengers to draw the APCs to the lymph nodes.
CD154Fas ligandCytokineChemokine

Question 2: After the APCs phagocytose pathogens, they usually migrate to the vast networks of lymph vessels and are carried via lymph flow to the draining lymph nodes (this network is collectively known as the ________).
Circulatory systemLymphatic systemSpleenImmune system

Question 3: Macrophages, which are also CD4+ and are therefore also susceptible to infection by ________.
AIDSHIV and AIDS misconceptionsSafe sexHIV

Question 4: An antigen-presenting cell (APC) or accessory cell is a cell that displays foreign ________ complex with major histocompatibility complex (MHC) on its surface.
Immune systemPhagocyteAntigenPolyclonal B cell response

Question 5: ________ may recognize this complex using their T-cell receptor (TCR).
T helper cellCytotoxic T cellRegulatory T cellT cell

Question 6: These professional APCs are very efficient at internalizing antigen, either by phagocytosis or by receptor-mediated ________, and then displaying a fragment of the antigen, bound to a class II MHC molecule, on their membrane.
Receptor-mediated endocytosisPotocytosisEfferocytosisEndocytosis

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