Acetylcholine receptor: Quiz

Question 1: The nAChRs are ligand-gated ________, and, like other members of the "cys-loop" ligand-gated ion channel superfamily, are composed of five protein subunits symmetrically arranged like staves around a barrel.
Cystic fibrosis transmembrane conductance regulatorSodium channelPotassium channelIon channel

Question 2: In myasthenia gravis, the receptor is targeted by ________, leading to muscle weakness.
AutoantibodyImmune systemAdaptive immune systemAntibody

Question 3: Like other ________, acetylcholine receptors are classified according to their "pharmacology", or according to their relative affinities and sensitivities to different molecules.
Membrane receptorMetabotropic receptorReceptor (biochemistry)Chemokine receptor

Question 4: The nAChR is found at the edges of junctional folds at the neuromuscular junction on the postsynaptic side; it is activated by ________ release across the synapse.
Kynurenic acidAcetylcholineKetamineDextromethorphan

Question 5: ________ has shown that the nicotinic and muscarinic receptors belong to distinct protein superfamilies.
Molecular biologyPost-transcriptional regulationTranscriptional regulationEpigenetics

Question 6: An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of ________, a neurotransmitter.
DextromethorphanKetamineAcetylcholineKynurenic acid

Question 7: nicotinic acetylcholine receptors (nAChR, also known as "ionotropic" acetylcholine receptors) are particularly responsive to ________
Nicotinic agonistNicotineLobelinePhencyclidine

Question 8: ________ (mAChR, also known as "metabotropic" acetylcholine receptors) are particularly responsive to muscarine.
5-HT receptor5-HT1A receptorHistamine H3 receptorMuscarinic acetylcholine receptor

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