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5-HT2A receptor: Quiz


Question 1: 5-HT2A also happens to be a necessary receptor for the spread of the human ________ called JC virus.
AdenoviridaeRotavirusParvovirus B19Polyomavirus

Question 2: ________ drugs like clozapine, olanzapine, quetiapine, risperidone are relatively potent antagonists of 5-HT2A as are some of the lower potency old generation/typical antipsychotics.
ZiprasidoneAtypical antipsychoticHaloperidolAripiprazole

Question 3: The gene has previously been called just HTR2 until the description of two related genes ________ and HTR2C.
5-HT2A receptor5-HT2B receptor5-HT1A receptor5-HT2C receptor

Question 4: [52] This polymorphism has also been studied in relation to ________ attempts, with a study finding excess of the C/C genotypes among the suicide attempters.
Death and cultureCremationSuicideEuthanasia

Question 5: Other antagonists are MDL-100,907 (prototype of another new series of 5-HT2Aantagonists) and ________.

Question 6: Other 5-HT2A agonists like LSD also have potent anti-inflammatory effects against ________-induced inflammation.
Fas ligandCD70B-cell activating factorTumor necrosis factor-alpha

Question 7: [21][22] Agonists acting at 5-HT2A receptors located on the ________ of pyramidal cells within regions of the prefrontal cortex are believed to mediate hallucinogenic activity.
Human brainCerebral cortexHippocampusApical dendrite

Question 8: This has led to the development of compounds such as AL-34662 that are hoped to reduce pressure inside the eyes but without crossing the ________ and producing hallucinogenic side effects.
Immune systemAIDSBlood-brain barrierMeningitis

Question 9: One effect of 5-HT2A receptor activation is a reduction in intraocular pressure, and so 5-HT2A agonists can be useful for the treatment of ________.

Question 10: [51] A weak link with an ________ of 1.3 has been found between the T102C polymorphism and schizophrenia.
Randomized controlled trialOdds ratioCorrelation and dependenceBlind experiment

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